Playlist

Introduction – Antigen Processing and Presentation

by Peter Delves, PhD

My Notes
  • Required.
Save Cancel
    Learning Material 2
    • PDF
      07 Slides Processing and Presentation of Antigen.pdf
    • PDF
      Download Lecture Overview
    Report mistake
    Transcript

    00:01 The vast majority of T-cells that is the alpha-beta (αβ) T-cells, need to see antigen that is processed and presented to them.

    00:09 So let’s explore together exactly what is meant by antigen processing and presentation.

    00:15 So T-cells recognize protein antigens that are processed into peptides.

    00:22 And what that means is that protease enzymes chop up the polypeptide chain into short stretches of amino acids - peptides. These peptides are then shown to the T-cell receptor or presented to the T-cell receptor by MHC molecules. So the peptide is put together with the MHC, and this combination of peptide-MHC is what the αβ T-cell needs to recognize.


    About the Lecture

    The lecture Introduction – Antigen Processing and Presentation by Peter Delves, PhD is from the course Adaptive Immune System.


    Included Quiz Questions

    1. Proteases process proteins into peptides for binding to the major histocompatibility complex molecules.
    2. Proteases bind peptides to major histocompatibility complex molecules.
    3. Proteases signal T cell receptors for binding to major histocompatibility complex molecules.
    4. Proteases strengthen the bond between the major histocompatibility complex molecule and the T cell receptor.
    5. Proteases act as antigens for binding to the major histocompatibility complex molecules.

    Author of lecture Introduction – Antigen Processing and Presentation

     Peter Delves, PhD

    Peter Delves, PhD


    Customer reviews

    (1)
    5,0 of 5 stars
    5 Stars
    5
    4 Stars
    0
    3 Stars
    0
    2 Stars
    0
    1  Star
    0