Okay so let's just review what we spoke about. These drugs are
used in major depressive disorder. Newer agents like the SSRI's
and the SNRI's have fewer side effects than the older drugs.
They are not more effective, they are as effective as the old drugs.
With the TCA's, one of the things we have to be aware of is
psychomotor retardation. And the most common side effect
is dry mouth. In terms of sleep disorders we are using the
shorter acting serotonin antagonists like trazodone.
Now the selected agents may be used in Parkinsonianism like
selegiline and that will be covered in our next lecture.
Chronic pain management,
amitriptyline which is the oldest of the TCA's, duloxetine
and venlafaxine. And of course diabetic neuropathy,
we often will use these medications as well.