Review – Antidepressants

by Pravin Shukle, MD

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    00:01 Okay so let's just review what we spoke about. These drugs are used in major depressive disorder. Newer agents like the SSRI's and the SNRI's have fewer side effects than the older drugs. They are not more effective, they are as effective as the old drugs.

    00:18 With the TCA's, one of the things we have to be aware of is psychomotor retardation. And the most common side effect is dry mouth. In terms of sleep disorders we are using the shorter acting serotonin antagonists like trazodone.

    00:34 Now the selected agents may be used in Parkinsonianism like selegiline and that will be covered in our next lecture.

    00:47 Chronic pain management, amitriptyline which is the oldest of the TCA's, duloxetine and venlafaxine. And of course diabetic neuropathy, we often will use these medications as well.

    About the Lecture

    The lecture Review – Antidepressants by Pravin Shukle, MD is from the course CNS - Pharmacology.

    Included Quiz Questions

    1. Amitriptyline is indicated for chronic pain.
    2. Tricyclic antidepressants have fewer side effects than selective serotonin reuptake inhibitors.
    3. Selegiline is often indicated for smoking cessation.
    4. Tricyclic antidepressants are rarely indicated in major depression.
    5. Duloxetine is not recommended for diabetic neuropathy.

    Author of lecture Review – Antidepressants

     Pravin Shukle, MD

    Pravin Shukle, MD

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