00:01 So in review, let's just go over what we talked about. 00:05 In major depressive disorder. 00:07 You can use any of these agents. 00:10 The newer agents like the SSRIs and the SNRIs have fewer side effects. 00:16 But they are not necessarily more effective than, say, the tricyclic antidepressants. Remember that you can have side effects that include psychomotor sedation with tricyclics. 00:25 You can also get sleep disturbances in using drugs like the serotonin antagonist like like trazodone. 00:33 But sometimes we will use that to our benefit and use it as a sleep aid. Selective agents may be used more predominantly in parkinsonism like selegiline. 00:45 You can use it in smoking cessation like bupropion. 00:48 You can use it in chronic pain syndromes like amitriptyline, duloxetine and venlafaxine, and you can use it in diabetic neuropathy like duloxetine. 00:57 So all of these drugs are excellent drugs. 01:01 Some of them are more excellent than others in certain disease states.
The lecture Review – Antidepressants by Pravin Shukle, MD is from the course CNS - Pharmacology.
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