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Wound Healing: Primary Intention – Inflammation and Wound Repair

by Carlo Raj, MD
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    Our topic here quickly will be through what's known as your wound healing. Wound healing at first will be primary intention. Now what that means is the fact that here with primary intention is the fact that the, let's say that you have taken a piece of paper and you've gotten yourself a paper cut. If you've gotten a paper cut you have created or introduced a wound, correct. In your skin. Now, if you have introduced a wound the edges of the wound might be far apart or they might be close together. If they are far apart, you will call that secondary intention. If there are close together it will be a primary intention. So the primary intention, you don't have to lay down as much granulation tissue. Think of this as being a pothole in a road. If it's a little pothole you can get away from you can get away with for the most part fibrosis, it bring the wound together, healing. But if the edges of the wound are far apart and now it's a knife wound, far apart. You need to put in alot of asphalt into the pothole to clean it up, right. To fix it. The asphalt of a pothole in a road is equivalent to granulation tissue. We'll talk about granulation tissue in great detail which includes the fact that it has collagen and it has angiogenesis with VEGF. All this is going to help you bring wounds back together. Once we get through the normal, we will go through some important in which you might lay down too much collagen. That will be a keloid. Or there might be deficiency of collagen such as Ehlers-Danlos. Let's begin. Day 1 you have a fibrin clot, a hematoma. Also keep in mind...

    About the Lecture

    The lecture Wound Healing: Primary Intention – Inflammation and Wound Repair by Carlo Raj, MD is from the course Cellular Pathology: Basic Principles.


    Author of lecture Wound Healing: Primary Intention – Inflammation and Wound Repair

     Carlo Raj, MD

    Carlo Raj, MD


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