Vitamin K

by Kevin Ahern, PhD

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    In this lecture, we’ll focus on two of the fat-soluble vitamins, vitamins K and E. And twp groups of molecules involved that what we call one-carbon metabolism, vitamin B12 and another group of molecules called the folates. Now, vitamin K is a fat-soluble vitamin that plays very important roles in the blood clotting process and also an important role in maintaining bone health. Like the other fat-soluble vitamins, vitamin K is stored in fat tissue. It is found very abundantly in green leafy vegetables like kale, spinach and collards. It’s a compound that’s stable in the air, but it does decompose when exposed to sunlight. There are several forms of vitamin K including natural forms that are found in nature and man-made forms that also appear to function in a similar fashion. Vitamin K-related modifications facilitate the binding of calcium to target proteins. And this is what really vitamin K’s function is in both the blood clotting process as well as in maintaining bone health. It’s the absence of vitamin K that leads to uncontrolled bleeding in an individual. Meaning of course that vitamin K is essential for the clotting process. A deficiency of vitamin K, however, is relatively rare in healthy adults. And it is required for bone formation. Vitamin K is actually a group of molecules. Now, the form known as vitamin K1 is also known as phylloquinone. It’s an electron acceptor that is found in plants in the photosynthesis system known as photosystem I. As I said, it’s found in the green leaves and because of the chlorophyll that the plants have, this compound is quite abundant in those plants. Vitamin K is involved in carboxylation. It is adding carboxyl group to the glutamates side chains of the blood clotting factors. This includes blood clotting factors II,...

    About the Lecture

    The lecture Vitamin K by Kevin Ahern, PhD is from the course Vitamins. It contains the following chapters:

    • Vitamins K, E, B12, and Folate Metabolism
    • Vitamin K Metabolism
    • Vitamin K Recycling

    Author of lecture Vitamin K

     Kevin Ahern, PhD

    Kevin Ahern, PhD

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