Vitamin B3, B5, B6 and B7

by Georgina Cornwall, PhD

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    Moving on now to vitamin B3, niacin. There's a little bit more to say about niacin that you need to know. Again it's involved in electron carriers as a cofactor. Also involved in nerve functioning. So naturally it has some critical roles. And finally we know that it's involved in cholesterol production. Now here I let you know that we have the vitamin B6 also coming into play. Because B6 is a cofactor for the enzyme that converts tryptophan to niacin. So a deficiency in B6 or tryptophan could also lead to a deficiency in niacin. So that's one thing to keep in mind. We'll again address it when we come to B6 of course. Because there's a reciprocal relationship there. Niacin excess is an interesting condition because often we use niacin to treat high cholesterol levels. So sometimes we'll see patients that have the symptoms of niacin excess. And one of the side effect is facial flushing. It's kind of a blotchy appearance. Very simple to alleviate though. We just remove B3 niacin because when we remove the B3, it will be removed, extra excess will be removed in urine. And the individual will return to normal. Niacin deficiency however, shows up as a condition called Pellagra. And the way that I remember the condition of pellagra is by using three Ds. Dementia, Diarrhea and Dermatitis. And the dermatitis often appears as cracked skin. Specially around the corners of the mouth. Now some people will call it four Ds because death could result. I prefer to stick with the three Ds. Because it's much less likely in the United States. But three Ds, dermatitis, dementia, diarrhea are signs of this pellagrin niacin deficiency. And you should understand those for your exam. Moving on to B5 which is pantothenic acid....

    About the Lecture

    The lecture Vitamin B3, B5, B6 and B7 by Georgina Cornwall, PhD is from the course Nutrition. It contains the following chapters:

    • Vitamin B3 - Niacin
    • Vitamin B7 - Biotin

    Author of lecture Vitamin B3, B5, B6 and B7

     Georgina Cornwall, PhD

    Georgina Cornwall, PhD

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