Vitamin B1 and B2

by Georgina Cornwall, PhD

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    Hello, this is the first in a series of two lectures on water soluble vitamins. We're going to explore the majority of the B vitamins in this lecture. We'll begin by looking at thiamin. Thiamin is B1. Why don't we just work our way straight through the numbers. In this lecture I'm going to highlight the parts that you need to know about each of these vitamins. Yes, there are many more potential functions. And things that you could know. But these are the highlights that you need for your exams. First of all vitamin B1, thiamin, is the most -- is a very important cofactor in many metabolic processes. You can see here for example, pryuvate dehydrogenase and alpha-ketogluterate, really depend on the B1 vitamin as a cofactor. This is found in many foods. And we fortify many foods with it also. And so we rarely see a deficiency in the United States. The one exception though is in the condition of alcoholism. Because often in alcoholism the majority of calories are coming from alcohol unless there is some deficiency in other nutrients. And so there are three conditions associated with B1 deficiency that you should be very clear about. Those three conditions are Dry Beri-Beri, Wet Beri-Beri and Wernicke Korsakoff. In dry beri-beri we have predominantly effects of the nervous system. We'll see things like symmetrical muscle wasting. So both sides are getting very weak. As well as peripheral neuropathy, confusions. Sometimes difficulty speaking and involuntary eye movements. So nystagmus would be constant in this case. So looking at someone's whose eyes are constantly shaking back and forth. Nystagmus would be a good indication of dry beri-beri and perhaps vitamin 1 deficiency. Wet beri-beri on the other hand has much more to do with cardiac systems. Individuals may...

    About the Lecture

    The lecture Vitamin B1 and B2 by Georgina Cornwall, PhD is from the course Nutrition. It contains the following chapters:

    • Water Soluble Vitamins and their Deficiencies
    • Vitamin B2 - Riboflavin

    Author of lecture Vitamin B1 and B2

     Georgina Cornwall, PhD

    Georgina Cornwall, PhD

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