Vascular Function Curves – Regulation of Venous Pressure

by Thad Wilson, PhD

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    To look at venous function curves or vascular function curves, they are sometimes referred to, we need to construct what they look like. So the veins are going to be what, from the venules to the veins to the large veins, this process involves getting blood back to the heart. It's more important to think about the speed at which you're getting blood back to the heart from the venous perspective because of the high capacitance veins have. Arteries don't have high capacitance so they pretty much act as rigid tubes and move fluid towards the tissue and then the veins. The veins have high capacitance which mean they can stretch so they can hold a lot of that fluid. So how do you construct this kind of curve? A vascular function curve is usually plotted with cardiac output on the X axis and center venous pressure on the Y. We have a couple of variables to go ahead and talk through. One is something called mean systemic filling pressure. What mean systemic filling pressure is? Is the pressure within the cardiovascular system if you shut the pump off. So there is no pumping action undergoing. At that point, you still have pressure within the system because there's still blood volume within the system. The other portion of a vascular function curve is there is a flat edge to the part that comes in to cardiac output. The reason why that happens is because veins can collapse. Veins don't just stay open, when you don't have pressure in them they will collapse. That's a distinct function of veins that doesn't happen with arteries who have enough structural integrity with things like collagen as well as vascularity and muscle that keep them open. So when we look at alterations in these...

    About the Lecture

    The lecture Vascular Function Curves – Regulation of Venous Pressure by Thad Wilson, PhD is from the course Vascular Physiology.

    Included Quiz Questions

    1. Increased blood volume
    2. Decreased blood volume
    3. Increased systemic vascular resistance
    4. Decreased systemic vascular resistance
    1. Veins
    2. Arteries
    3. Capillaries
    4. Arterioles
    5. Coronary arteries

    Author of lecture Vascular Function Curves – Regulation of Venous Pressure

     Thad Wilson, PhD

    Thad Wilson, PhD

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