Steroid Hormone Receptors

by Carlo Raj, MD

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    Let’s talk about steroid hormones please. Now, steroid hormones, you want think of this as being a separate topic only because its mechanism is a little bit different. It's quite interesting here. You're going to like this. Watch. Let’s talk about steroid hormones, specifically adrenal cortex. Are we there now? Before we get to the adrenal cortex, couple of things that you want to keep in mind is when would you release or how would you release some of these hormones from the adrenal cortex. ACTH. Coming from where? Anterior pituitary. What’s the name of the releasing hormone? Corticotropin releasing hormone. Good. Now, ACTH is going to kick start the synthesis of your adrenocortical hormones. The next thing which you want to do is give yourself an acronym, right? Give yourself an acronym for the adrenal cortex. GFR. Remember, now with the adrenals, you want to divide it into two separate structures. What is that? The cortex and the medulla. The cortex and the medulla. The medulla is always in the inner aspect; the cortex, obviously, outer. The outer aspect of the adrenal is known as adrenal cortex. You will divide that into GF and R if you haven't done so already. The G stands for zona glomerulosa. F stands for zona fasciculata. R stands for zona reticularis. F stands for zona fasciculata. R stands for zona reticularis. You might've heard of the phrase, the deeper I go, the sweeter it gets. What am I referring to? The deeper you go, adrenal cortex, the zona reticularis, I am going to release sex hormones. The glomerulosa, you’re releasing what? Aldosterone. Mineralocorticoid. From your fasciculata, what are you releasing? Glucocorticoid. Deeper I go, sweeter it gets. Reticularis, I am releasing androgens. Where are the receptors? In general, whenever you deal with steroid...

    About the Lecture

    The lecture Steroid Hormone Receptors by Carlo Raj, MD is from the course Introduction to the Endocrine System.

    Included Quiz Questions

    1. Zona fasciculata - glucocorticoid receptor
    2. Zona glomerulosa - glucocorticoid receptor
    3. Zona fasciculata - mineralocorticoid receptor
    4. Zona reticularis - mineralocorticoid receptor
    5. Zona glomerulosa - androgen receptor
    1. Androgen receptor
    2. Estrogen receptor
    3. Vitamin D receptor
    4. Thyroid hormone receptor
    5. Retinoic acid receptor
    1. Vitamin D - calcitriol
    2. Thyroid hormone - T4
    3. Vitamin D - PDH
    4. Estrogen - prolactin
    5. Thyroid hormone - retinoic acid
    1. Retinoic acid receptor
    2. Vitamin D receptor
    3. Androgen receptor
    4. Mineralocorticoid receptor
    5. Glucocorticoid receptor

    Author of lecture Steroid Hormone Receptors

     Carlo Raj, MD

    Carlo Raj, MD

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