00:01
So let’s wrap up sedative hypnotics.
00:03
These are drugs that depress the central nervous system.
00:07
Most often we use them to treat anxiety and difficulty sleeping or insomnia.
00:12
Now there's three main groups of sedative hypnotics:
benzodiazepines, benzodiazepine-like drugs, and barbiturates.
00:20
We focus on benzodiazepines because they're safer than barbiturates,
there's less risk of developing tolerance and physical dependence.
00:28
There's lower risk of respiratory depression unless you use it with other CNS depressants.
00:34
So remember, don’t kick back a benzodiazepine with the big beer.
00:39
Examples of benzodiazepine drug names include Alprazolam, Clonazepam, Diazepam -
which you probably recognize as Valium; Lorazepam and Temazepam.
00:50
Common side effects are sedation.
00:53
Remember these are sedative-hypnotic drugs, so if you’ll kinda sleepy,
maybe a little light-headed, tired, drowsy, a little bit confused
and some anterograde amnesia - that’s short-term memory loss when you took the medication.
01:06
It’s not safe to drink alcohol or take opioid medications in addition to benzodiazepines.
01:12
While the benzodiazepines have a lower risk for abuse there's still a potential for abuse.
01:19
Now Flumazenil is a benzodiazepine receptor antagonist
which is really useful if you're having to treat acute overdose of benzodiazepines.
01:28
Remember to wean benzodiazepines and all Central Nervous System medications slowly.
01:34
You don’t wanna abruptly discontinue them otherwise your patient will experience
some very uncomfortable withdrawal symptoms.
01:42
Thank you for watching our video today.