Our topic here is seborrheic keratosis.
A common epidermal tumor consisting
of a benign proliferation of
Very common in the elderly.
Greater than 65% of
persons older than 80
may have quite a number of these
seborrheic keratosis or keratoses.
Thought to be inherited in an autosomal
It could be inherited in terms and with
cherry angioma also being associated.
Possesses absolutely no
The sign of Leser-Trélat is a rare
Abrupt appearance of multiple
Associated with a variety of malignancies,
including gastrointestinal and lung cancers
Seborrheic keratosis in this case,
Morphology would be
Literally like taking a piece of chocolate
and putting it on a person’s back.
We call this
brown in appearance.
Well, requires really no treatment.
Seborrheic keratosis, SK,
doesn’t require a treatment.
If inflamed, traumatized or
they may be destroyed.
Seborrheic keratosis not to be
confused with seborrheic dermatitis
and definitely not to be confused with, later
on, we’ll talk about actinic keratosis.
You see as to how terminologies --
everything in derm.
What does that mean to you?
Thickened epidermis with
sharply demarcated base.
It looks like, as I told you earlier,
a piece of chocolate that
has been placed on the back
and therefore if you take a
look at the histology here,
It will be sharply demarcated because of
increased thickness of your keratinocytes.
Hyperkeratosis, as you can see
in the histologic picture here.
Here, we move on to actinic
keratoses or actinic keratosis.
Pause here for a second
and make sure that you know that
our topic is actinic keratosis
So what does actinic
keratosis mean to you?
This is premalignant.
Is that clear?
rally no chance of
going on to malignancy.
So if you’re thinking about malignancy,
then you’re thinking about on
your skin exposure to UV rays.
So therefore, actinic keratosis is
premalignant caused by UV exposure.
Have a potential to move on --
Now of the type of skin cancers that
we will discuss in this section,
which will then include squamous
cell cancer, which is our topic,
squamous cell cancer of the
skin or cutaneous squamous cell
is what you must think of actinic
keratosis as being premalignant too.
Is that clear?
Clinically feels gritty,
like sand paper.
as far as the skin is concerned,
what kind of cells are these?
So therefore, upon
exposure to UV rays,
maybe premalignant condition such as
actinic as you see in the picture here
and worst case scenario,
may go on to squamous
cell cancer of the skin.
Our first true