00:00
Now let's take a look at asthma.
00:02
It's pretty common, you see
it diagnosed in children.
00:05
I'm sure some of you watching this video today
have either experienced asthma in yourself
or someone in your life
has asthma.
00:13
Now there's two things I want you to
underline first off in your notes.
00:17
First is bronchoconstriction, that word.
00:19
Put a big underscore around
it, circle it and star it.
00:23
Because that's one-half of the
problem with asthma.
00:27
The other half of the
problem is inflammation.
00:31
Inflammation is an immune response and it's triggered
by these allergens that you're exposed to.
00:36
Now, each one of us has specific allergens that
cause that inflammatory response in our body.
00:42
It may be something like dust or maybe
it is pet dander or something outside
when a certain flower
or trees are blooming.
00:50
But it's really important part of educating your
patient for them to identify what are their triggers.
00:56
We can try to avoid them or at the very least
pre-medicate before they're exposed to their triggers.
01:01
So what happens when you
get exposed to something
that you're allergic to,
that you have inflammatory response to,
is that the airways
become inflammed.
01:11
Inflammed airways are smaller airways and
that makes breathing more difficult.
01:16
So the bronchoconstriction, when
that thing's clamping down.
01:20
But inflammation means that those airways are
even becoming smaller in diameter on the inside,
so it is definitely double trouble.
01:28
Now it don't just become inflammed and
smaller and what we have left to work with
gets filled with all
this excess, nasty mucus.
01:36
So you have a narrowed airway, you
got the vessels clamping down,
you've got that smooth muscle
clamping down,
the airways are inflammed,
narrowed and full of mucus.
01:47
Okay, so I wanna give you a few more of the
steps and exactly what happens in your body
when you're exposed to an allergen and
how you end up with those airways
that are smaller and full of gunk.
01:59
When you understand how this happens,
it'll make more sense to you
on why we choose which medications
that we do to treat asthma.
02:06
So you go for a walk, you're exposed
to an allergen, some flowering tree
and you start to get that feeling where
you're having a hard time breathing.
02:15
But what's going on?
The allergen is breathed into your body and
it binds to IgE antibodies on mast cells.
02:23
Now when IgE antibodies connect to the
mast cells, then the mast cells,
they release their mediators: histamines,
leukotrienes, interleukins and prostaglandins.
02:36
Now those first two might
sound kinda familar to you.
02:39
Histamines are the one that cause
all that response in your body.
02:43
That's why we take some other medications
called antihistamines for allergic reactions.
02:48
Antihistamines will block the histamines
that's released from these mast cells
from connecting to the receptors.
02:56
Okay, so you've exposed
to an allergen, Step 1.
03:00
Then when those allergens combine
the IgE and connect the mast cells,
mast cells release those beasts: histamine,
leukotrienes, interleukins and prostaglandins.
03:10
So, when these things are released in your body,
that's what causes the bronchoconstriction,
the inflammatory cells to be infliltrated, now you
got the eosinophils, leukocytes and macrophages.
03:21
These all happens, boom!
in seconds.
03:25
But I want you to get the process:
exposed to the allergen, IgE antibodies
connect to that to the mast cell,
mast cells then release
their mediators.
03:34
The mediators are what wreak havoc if
they can hit their receptors.
03:39
And then those
inflammatory cells respond
and release their cytokines and
leukotrienes and interleukins.
03:44
So it's a chain effect
on what goes on.
03:47
End result?
the airways are hyperactive,
inflammed and have excess mucus.
03:53
Now, is it important that you
memorize each one of these steps?
Not really at this point.
03:58
I just want you to understand the
concept, the inflammatory part of asthma.
04:03
They're exposed to an allergen and that
with IgE antibodies, hook into those cells,
spraying out their nasty beast
and that's what ends up
with the hyperreactive, inflammed,
excess mucus in our airways.
04:18
Okay.
04:19
Now when we talked about some of the
other medications we talked about,
we can intervene certain steps, we can
prevent this bad result at the end.
04:27
That's the takeaway point
from this topic.
04:30
Knowing that these things are released,
things follow a very sequential order,
then you'll understand when we use these
specific medications, we can stop that reaction
and have airways that are more open with
less mucus because that's our goal.
04:46
Now if you've ever experienced asthma,
I want you to get a little feel
for what it feels
like for the patient.
04:52
If you have experienced asthma, you're
gonna know exactly what I'm talking about.
04:57
Because when they start to have
triggers that can lead to a bronchospasm,
I don't want you to think sometimes it's just like
a short, this can't really catch their breath.
05:07
No, this is intense and the feeling
of not being able to breathe
will cause panic in even
the most calm patient.
05:16
Because these airways before they even are exposed
to allergen are probably already narrowed.
05:21
Their chest feels really tight
is how people explain it to us.
05:26
It's hard for them to catch their
breath or to take a deep breath in
and their breath sounds will have wheezes,
or this high pitched whistling sounds
when they try to take a breath.
05:35
(wheeze)
They'll sound kind of like that.
05:39
Sometimes you'll need a
stethoscope to hear them
but usually when someone's having
a pretty serious asthma attack,
you can hear it even
without a stethoscope.
05:47
I've been at the gym with someone who's having
an asthma attack while we're working out
and I promise you, even on my bad side, I
can hear somebody wheezing a ways away.
05:57
So I'm always asking,
do you have your medicine?
Do you have your inhaler?
So recognize, be alert and watch for those signs and
symptoms of a patient having an asthma attack.
06:07
They also might have this cough that they
just can't get rid of during this attack.
06:11
It'll be irritated, not because
those airways are being inflammed.
06:15
They also might feel
dizzy or light headed
which is an especially bad
combination at the gym.
06:22
So why is it important that you learn
all the signs of an asthma attack?
Or when a patient is starting
to go into an asthma attack?
Because when we give them medications to treat
that attack, these things should be lessened.
06:36
It is very important as a nurse
that you know how to evaluate
the effectiveness of
medication treatment plans.
06:42
So if I have an asthma patient,
who's feeling like this,
I'm gonna ask after they've taken their medication
or when we're working through the process with him,
"Do you feel like you can catch
your breath better now?"
I'll be listening to see
if wheezing is going away.
06:57
I'll ask him if their chest
still feels as tight.
07:00
I'll be observing to see if
that cough has lessened.
07:03
So you always want to understand
what are the signs and symptoms
when things are not going well for you
patient so you know which medication to pick
and so you know how to evaluate
if that medication was effective.