Overview – Reproductive Pharmacology

by Pravin Shukle, MD

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    00:01 Welcome to Pharmacology by Lecturio.

    00:03 I'm Dr. Pravine Shukle.

    00:05 We're going to be covering some reproductive pharmacology today.

    00:09 Listen, this is a huge topic.

    00:12 You can see all the different subtypes and categories on the screen beside me.

    00:17 The gonadal hormone antagonists and agonists sometimes do the same thing and sometimes they do the opposite thing of what you expect.

    00:24 We're going to spend a lot of time in each section and we're going to go over them in detail, so that you understand them and you feel confident answering questions on exams.

    00:33 We're going to be talking about estrogens and anti-estrogens.

    00:37 We’ll be talking about progestins and anti-progestins and we're going to be talking about androgens and anti-androgens.

    00:44 With respect to the anti-estrogen medications, there's a whole bunch of subtypes there.

    00:49 There are the receptor antagonists.

    00:52 There are aromatase inhibitors and then there are GnRH agonists, like danazol, and antagonists, which interestingly enough do the same thing.

    01:02 Underneath the receptor antagonist section – this is estrogen receptor antagonists – we have full antagonists and we have selective antagonists.

    01:13 With respect to the progestins, we have actual progestin that we administer and we have an anti-progestin called mifepristone.

    01:21 With respect to the androgens, we have a whole list of medications.

    01:25 We have anti-androgens that are receptor antagonists.

    01:29 We have 5-α-reductase inhibitors.

    01:32 We have synthesis inhibitors.

    01:34 And we have other ones such as the GnRH agonists and antagonists.

    01:40 When we take a look at reproductive pharmacology, just have a look at this diagram.

    01:44 I won't go over it in detail now because each section of this diagram will be placed beside the specific area that we’re talking about.

    01:52 This just gives us an overview.

    01:54 So, have a look at it on your own time.

    01:55 It's a very good diagram to understand how all of the drugs fit in.

    About the Lecture

    The lecture Overview – Reproductive Pharmacology by Pravin Shukle, MD is from the course Reproductive Pharmacology.

    Included Quiz Questions

    1. GNRH-FSH/LH-estrogen/progesterone
    2. Estrogen/progesterone-FSH/LH-GNRH
    3. FSH/LH-GNRH-estrogen/progesterone
    4. Estrogen/progesterone-GNRH-FSH/LH
    5. GNRH-Estrogen/progesterone-FSH/LH
    1. Tamoxifen
    2. Fulvestrant
    3. Anastrozole
    4. Flutamide
    5. Finasteride

    Author of lecture Overview – Reproductive Pharmacology

     Pravin Shukle, MD

    Pravin Shukle, MD

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    Nice summary
    By Hatem Q. on 01. February 2019 for Overview – Reproductive Pharmacology

    Brief and clear introduction, which to get you prepared for the details Great summary to come back for a fast review and memorizing