Sarcoidosis is a multisystem inflammatory disease that causes noncaseating granulomas. The exact etiology is unknown. Sarcoidosis usually affects the lungs and thoracic lymph nodes, but it can also affect almost every system in the body, including the skin, heart, and eyes, most commonly. Acutely, sarcoidosis presents with lymphadenopathy, fever, malaise, joint pains, a panniculitis on the shins known as erythema nodosum, and occasionally cough and shortness of breath. Chronic pulmonary sarcoidosis presents with an insidious onset of dyspnea, cough, chest pain, and a variety of other symptoms depending on the organ systems involved. Diagnosis often requires a biopsy of the granulomas. Management includes observation, NSAIDs, glucocorticoids, and potentially one of several steroid-sparing agents. Acute sarcoidosis is usually self-limiting with an excellent prognosis, but chronic sarcoidosis can lead to severe pulmonary fibrosis.