So let's wrap up what we know about these hormones. Estradiol is the main endogenous estrogen.
That's the estrogen that my body makes. Progesterone is the main progestational hormone.
Both hormones are produced in the ovaries and both hormones cause significant changes in the uterus.
Estrogen can be given multiple different routes; oral, transdermal, intravaginal, and then rarely
IV or IM. Now the risk for estrogen and progestin therapy include increased risk for clots
particularly with older people, DVT, stroke or pulmonary embolism are what those clots lead to.
May have an increased risk of dementia for women greater than 65 years of age. It may increase
the risk for breast cancer. So we've got some pretty significant risk there; clots, stroke, MI,
embolism, increased risk for dementia, possible increased risk for breast cancer. So these are
not drugs to just start taking lightly. You want to make sure that you have a full history and
you have a long conversation with a healthcare provider to be very aware of your family history,
your personal history, the risk and benefits of this type of treatment. Now after conception,
progesterone primarily maintains the pregnancy. Progesterone is P and pregnancy is P. Thank
you for watching our video today.