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Principle of Independent Assortment – Classic Mendelian Genetics

by Georgina Cornwall, PhD

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    00:00 So, round and wrinkled, yellow and green, purple and white, all move separately from each other.

    00:07 Well, this is because they were indeed on separate chromosomes and so we have very nice pattern that results but the point is he was able to come to the principle of independent assortment.

    00:23 So, from the model hybrid cross, we got segregation.

    00:27 The principle of independent assortment is saying, "Yes. Segregation happens but each trait does so independently of the other trait." So, the principle of independent assortment states that, in our language of meiosis and chromosomes, during meiosis I, chromosome alignment is random on the metaphase plate such that these chromosomes can segregate from each other, independently of other factors.

    01:00 So, when we do take a look at meiosis, we can see that it's this random alignment of chromosome pairs on the metaphases plate of meiosis I that really support Mendel's principle of independent assortment.

    01:16 Again, each pair segregates from each other independently of the next pair because they align randomly on the metaphase plate where we can have all the blue ones on one side, all the red ones on the other side or some shuffling of that same layout where we're just having two separate from each other.

    01:40 In closing the first lecture introducing us to genetics and exploration of Mendel, you should now be able to describe what we knew before Mendel as well as evaluate the outcomes of mono and dihybrid crosses.

    01:54 We should be able to relate these to movement of chromosomes during meiosis as well as differentiate between the principle of segregation and the principle of independent assortment.

    02:08 Thank you so much for listening.

    02:10 I look forward to seeing you in the next lecture.


    About the Lecture

    The lecture Principle of Independent Assortment – Classic Mendelian Genetics by Georgina Cornwall, PhD is from the course Understanding Genetics.


    Included Quiz Questions

    1. Factors segregate from each other independently of any other factors.
    2. The principle of independent assortment.
    3. Meiosis involves chromosomes separating from each other to form gametes.
    1. The genes located on the different chromosomes are transmitted independently of each other from one generation to another.
    2. The genes present in the same chromosomes are transmitted independently of each other from one generation to another.
    3. The genes present on the same side of chromosome arm are transmitted independently of each other from one generation to another.
    4. The genes present near the centromere of the chromosome is transmitted independently of each other from one generation to another.
    5. The genes located on the different chromosomes are transmitted together from one generation to another.

    Author of lecture Principle of Independent Assortment – Classic Mendelian Genetics

     Georgina Cornwall, PhD

    Georgina Cornwall, PhD


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