Playlist

Pituitary Case: 48-year-old Woman with Weight Gain, Easy Bruising, and Hypertension

by Michael Lazarus, MD

My Notes
  • Required.
Save Cancel
    Learning Material 2
    • PDF
      Slides Adrenal-Pituitary.pdf
    • PDF
      Download Lecture Overview
    Report mistake
    Transcript

    00:01 Let's discuss another case.

    00:03 A 48-year old woman is seen for weight gain, easy bruising, hypertension, and worsening diabetes control.

    00:11 She takes metformin and lisinopril.

    00:14 On exam, she has a blood pressure of 172 over 90, a heart rate of 77 beats per minute, and a BMI of 35.

    00:24 She has centripetal obesity with livid stria, a supraclavicular and posterior neck fat pad, as well as hirsutism on her chin and anterior neck.

    00:36 Her labs show 24-hour free cortisol of 200 micrograms in 24 hours, a midnight salivary cortisol of 300 nanograms per ml, and an ACTH level of less than five picograms per ml.

    00:52 What is the diagnosis? In reviewing this fairly complex presentation, there are some signs and symptoms that are worth noting.

    01:01 First of all, these signs and symptoms suggest cortisol excess.

    01:05 This is manifested as weight gain, bruising, hypoglycemia, hypertension, centripetal wall fat distribution, the presence of stria, and hirsutism.

    01:17 Also, the labs show increased cortisol and a suppressed ACTH.

    01:22 This woman clearly has Cushing syndrome.


    About the Lecture

    The lecture Pituitary Case: 48-year-old Woman with Weight Gain, Easy Bruising, and Hypertension by Michael Lazarus, MD is from the course Pituitary and Hypothalamic Disorders.


    Included Quiz Questions

    1. Cushing syndrome
    2. ACTH-secreting pituitary adenoma
    3. Prolactinoma
    4. Polycystic ovary syndrome
    5. Fatty liver disease attributable to diabetes

    Author of lecture Pituitary Case: 48-year-old Woman with Weight Gain, Easy Bruising, and Hypertension

     Michael Lazarus, MD

    Michael Lazarus, MD


    Customer reviews

    (1)
    5,0 of 5 stars
    5 Stars
    5
    4 Stars
    0
    3 Stars
    0
    2 Stars
    0
    1  Star
    0