00:01 Let us now take a look at Pill-Induced Esophagitis. 00:04 At this point, we’ve completed a discussion of our reflux with GERD and Barrett’s. 00:12 What kind of pills might you be taking? Well here, when you’re swallowing a pill, focal damage in the mid-esophagus because of the exposure of the pill there more so. 00:23 Prolonged stasis of certain meds in the esophagus may then cause it. 00:28 Here, your focus should be on potassium compounds, NSAIDs for sure. 00:33 In addition, there’s quinidine, iron, maybe a patient is taking alendronate due to osteoporosis, tetracycline, vitamin C; all this could be pill-induced esophagitis. 00:47 This condition occurs most commonly in the elderly, and there are several factors thought to be involved. 00:52 These include decreased salivary production, swallowing the pill while in the recumbent position, falling asleep shortly after taking the medication, and insufficient water intake with the pill. 01:02 Treatment for this condition usually starts with discontinuation the offending medication. 01:07 Sometimes the medication is one that can’t be stopped, and in those instances, encouraging lifestyle modifications can be helpful. 01:14 These would include taking the pill with a full glass of water, remaining upright for some period of time after ingesting the pill, and not taking the medication right before bedtime. 01:22 A short course of a PPI or antacid can also help prevent mucosal irritation from excess acid. 01:28 Oral sucralfate can be used to help form a protective barrier and avoidance of potentially irritating foods maybe helpful as well.
The lecture Pill–Induced Esophagitis by Carlo Raj, MD is from the course Esophageal Disease: Basic Principles with Carlo Raj.
A 60-year-old man comes to your clinic because he has had discomfort in his throat for the past 2 days. He was given painkillers for his osteoarthritis. What is the MOST likely cause of his throat discomfort?
Which combination of drugs is NOT associated with inflammation of the esophagus?
A 75-year-old woman with a history of osteoporosis comes to your office. She has been taking a bisphosphonate drug (alendronate sodium) and complains of difficulty swallowing for the past 2 days. What is the MOST likely cause?
5 Stars |
|
5 |
4 Stars |
|
0 |
3 Stars |
|
0 |
2 Stars |
|
0 |
1 Star |
|
0 |