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Pertussis: Etiology and Pathology (Pediatric Nursing)

by Paula Ruedebusch

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    00:01 Now, let's talk about pertussis.

    00:03 Pertussis, also known as whooping cough, is a highly contagious respiratory disease.

    00:09 It is caused by the bacterium <i>Bordetella pertussis</i>.

    00:14 Pertussis can cause problems for a really long time.

    00:18 The symptoms can last for at least 10 weeks.

    00:22 It can cause uncontrollable, violent coughing, and since it's a bacterial disease, we can treat it with antibiotics.

    00:30 Pertussis is vaccine-preventable.

    00:33 In infants and young children, the DTaP vaccine is given at the 2-month, 4-month, 6-month, 15-18 month, and the 4-5 year well child checks.

    00:47 Older children and adults will be boosted with a TDaP vaccine that also contains pertussis, or whooping cough, coverage.

    00:55 <i>Bordetella pertussis</i> is a fastidious, gram-negative bacterium requiring a special media for isolation.

    01:04 Now, pertussis.

    01:05 The etiology.

    01:06 It's a very contagious disease, spread from person to person by coughing or sneezing, or even just sharing a breathing space.

    01:14 The droplets that contain the <i>Bordetella pertussis</i> bacteria can be spread up to 6 feet,and can live on surfaces, like counter tops and doorknobs for days.

    01:26 Many babies who get pertussis are infected by older siblings, parents, or caregivers, who may not even know that they have this disease yet.

    01:35 Infected people are most contagious from the onset, through about the first 3 weeks after the start of the paroxysmal coughing.

    01:44 Antibiotics may shorten the amount of time that someone is contagious, but it will not take away their cough.

    01:51 So pertussis is a primarily toxin-mediated disease.

    01:56 This means the gram-negative pertussis bacteria droplets will enter your patient and attach to the cilia of the respiratory epithelial cells.

    02:05 The bacteria are going to produce multiple antigenic and biologically active toxins and products that cause damage to the cilia, and they cause these airways to swell.

    02:15 Now, this makes it hard for the patients to clear their pulmonary secretions because there's inflammation and decreased ciliary action, and the infection can further invade down into the surrounding tissues.


    About the Lecture

    The lecture Pertussis: Etiology and Pathology (Pediatric Nursing) by Paula Ruedebusch is from the course Respiratory Disorders – Pediatric Nursing. It contains the following chapters:

    • Pertussis – Fundamentals
    • Pertussis – Etiology
    • Pertussis – Pathology

    Included Quiz Questions

    1. 2–3 weeks after the cough begins
    2. 2–3 days after the cough begins
    3. 3–5 weeks after the cough begins
    4. 3–5 days after the cough begins
    1. Gram-negative
    2. Gram-positive
    3. Gram-neutral
    4. Gram-regenerative

    Author of lecture Pertussis: Etiology and Pathology (Pediatric Nursing)

     Paula Ruedebusch

    Paula Ruedebusch


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