In order to respond to an infection,
lymphocytes need to become activated.
So we’re going to look
at lymphocyte activation.
The lymphoid tissues can be divided
into primary lymphoid tissues where the
lymphocytes develop and secondary lymphoid
tissues where they become activated.
Hematopoietic stem cells in the bone marrow
give rise to the B-lymphocytes within the bone
marrow itself, whereas those cells that are going
to become T-lymphocytes travel to the thymus.
The B-lymphocytes and T-lymphocytes leave the primary
lymphoid tissues once they reach maturity and travel to the
secondary lymphoid tissues which are the lymph nodes, the
spleen and the mucosa-associated lymphoid tissue or MALT.