This is a normal bone marrow.
First, I would like for you to take a
look at the periphery on your upper left
and down on the lower right,
those are lipid vacuoles, okay?
Lipid vacuoles, hence,
they are nice and clear.
That’s when you know that you’re
in your bone marrow, right?
Versus your cortical
bone which is solid
and you would never find
such a lipid vacuoles
in the cortical or the
pillars of your bone.
With the bone marrow, empty space.
So now what you find between those
lipid vacuoles are all these cells.
And this is a normal bone marrow.
And what these cells that you’re
looking at are all blasts.
Now, what kind of blasts?
It's rather difficult to say.
You probably have
normal blasts in there.
You could have megakaryocytes in there,
but all of your normal stem cells
that you would expect to be containing
producing different types of cells
that obviously we require for
proper, proper functioning.
So this is normal and our
topic is aplastic anemia,
then what can you expect these cells
or would you these cells to be here?
And so therefore, take a look
at this, it is hypocellular.
What you’re seeing in the middle
there is completely empty.
All that you see there
is lipid vacuoles.
This is not normal.
And so therefore, what kind
of anemia would this be?
Obviously, a normocytic
because you can’t even produce any RBCs
and not to mention, this
will be pancytopenia.
There is nothing to destroy.
Except for the bone marrow has been lost.