00:01 Monoamine oxidase inhibitors actually do have some blood pressure activity. 00:07 Remember that MAOs cause a false transmitter. 00:11 They do cause lowering of blood pressure. 00:14 In fact, even in patients who are using monoamine oxidase inhibitors for depression will have a reduction in blood pressure. 00:23 In fact, if you take a look at your psychiatric medication lecture, and today's lecture, you'll see that I stole this image from the psychiatry lecture. 00:33 Now, one of the things I mentioned to you before in the psychiatry lecture is Foods high in tyramine like cheese and wine can cause a release of a large amount of noradrenaline, or norepinephrine. 00:46 And this can cause a large increase in blood pressure. 00:49 Have a look at that other lecture in antidepressants, and you can see how that works. 00:56 Now, these drugs have frequent side effects, they're not very effective and as I said before, they're not used a lot. 01:02 Once again, doctors hate these drugs for hypertension and never think about it. 01:07 but pharmacologist love these drugs and put them on exams in the hypertension section. 01:12 I'm not going to say that about its use in depression because in depression, we do use them more than we do in hypertension.
The lecture Monoamine Oxidase Inhibitors – Drugs in Hypertension by Pravin Shukle, MD is from the course Cardiovascular Pharmacology. It contains the following chapters:
Why should patients on MAOIs not eat cheese or drink wine?
Which statement regarding monoamine oxidase inhibitors is most accurate?
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