Beautiful table here for
you to take a look at.
It summarizes all of
your microcytic anemias.
Here they are, iron deficiency.
What you’re seeing here in green is quite
important for you to pay attention to.
But you should be able to walk through
each and every single one of these labs.
And once you do, I’m not going
to go through this again.
But all of this go through the green ones.
there is going to be increased in
red blood cell distribution width.
What does that mean?
No uniformity, all different sizes.
And with iron deficiency anemia, you will
find increase in total iron binding capacity
because the ferritin is decreased.
Anemia of chronic disease, here you will
find either normal or increased ferritin.
The opposite of iron deficiency anemia.
Why might it would be increased?
Remember anemia of chronic disease, give
me the 2 categories that you will this in?
It will either be in normocytic
and may remain there.
Or it might be microcytic as we see here.
Thalassemia, iron studies are normal
and your RBC count maybe
but usually it will be
variable so be careful there.
And red blood cell distribution
width will be increased here.
Otherwise, take a look at your
iron studies thalassemia.
Yeah, perfectly normal,
alpha or beta, right?
Next, sideroblastic, what does this mean?
Give me the most common acquired?
Give me the one in which
maybe a child or a baby
was crawling towards paint
chips and eating it.
Good. Lead poisoning.
And what if there is a patient that have
tuberculosis taking INH without B6?
Good, there it is, INH
And what’s the rate-limiting enzyme
in the porphyria pathway?
ALA synthase and genetically,
you might be missing that.
You’ll begin with iron
overload for the most part.
Okay, remember ring sideroblasts.