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Microcytic Anemia: Summary

by Carlo Raj, MD
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    00:01 Beautiful table here for you to take a look at.

    00:02 It summarizes all of your microcytic anemias.

    00:07 Here they are, iron deficiency.

    00:10 What you’re seeing here in green is quite important for you to pay attention to.

    00:13 But you should be able to walk through each and every single one of these labs.

    00:19 And once you do, I’m not going to go through this again.

    00:20 But all of this go through the green ones.

    00:24 Iron deficiency, there is going to be increased in red blood cell distribution width.

    00:26 What does that mean? No uniformity, all different sizes.

    00:30 And with iron deficiency anemia, you will find increase in total iron binding capacity because the ferritin is decreased.

    00:36 Anemia of chronic disease, here you will find either normal or increased ferritin.

    00:45 The opposite of iron deficiency anemia.

    00:46 Why might it would be increased? Remember anemia of chronic disease, give me the 2 categories that you will this in? Good.

    00:53 It will either be in normocytic and may remain there.

    00:58 Or it might be microcytic as we see here.

    01:01 Thalassemia, iron studies are normal and your RBC count maybe perhaps increased but usually it will be variable so be careful there.

    01:10 And red blood cell distribution width will be increased here.

    01:13 Otherwise, take a look at your iron studies thalassemia.

    01:14 Yeah, perfectly normal, alpha or beta, right? Next, sideroblastic, what does this mean? Give me the most common acquired? Good. Alcohol.

    01:25 Give me the one in which maybe a child or a baby was crawling towards paint chips and eating it.

    01:31 Good. Lead poisoning.

    01:34 And what if there is a patient that have tuberculosis taking INH without B6? Good, there it is, INH poisoning, right? And what’s the rate-limiting enzyme in the porphyria pathway? ALA synthase and genetically, you might be missing that.

    01:50 You’ll begin with iron overload for the most part.

    01:51 Okay, remember ring sideroblasts.


    About the Lecture

    The lecture Microcytic Anemia: Summary by Carlo Raj, MD is from the course Microcytic Anemia – Red Blood Cell Pathology (RBC).


    Included Quiz Questions

    1. Ferritin
    2. RBC count
    3. None of these
    4. Serum Iron
    5. MCV

    Author of lecture Microcytic Anemia: Summary

     Carlo Raj, MD

    Carlo Raj, MD


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    Great lecture
    By Sana Q. on 26. March 2018 for Microcytic Anemia: Summary

    Thank you Dr Raj, it was a very good lecture and your humor was keeping me interested in the topic.

     
    Hematology Anemia
    By Odette H. on 12. December 2017 for Microcytic Anemia: Summary

    It is was precise and clear lecture of anemias.. Thank you so much Dr. Raj!