Lectures

Major Histocompatibility Complex (MHC) and MHC Disparity

by Peter Delves, PhD
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    About the Lecture

    The lecture Major Histocompatibility Complex (MHC) and MHC Disparity by Peter Delves, PhD is from the course Transplantation Immunology. It contains the following chapters:

    • A Closer Look at the Major Histocompatibility Complex
    • MHC Disparity between Individuals

    Included Quiz Questions

    1. HLA-B
    2. HLA-A
    3. HLA-C
    4. HLA-DQ
    5. HLA-DR
    1. Antigen Presenting Cells
    2. Macrophages
    3. B cells
    4. Dendritic Cells
    5. Thymic epithelium
    1. DP, DQ, and DR α chains are equally polymorphic
    2. Genes are located on chromosome 6
    3. Genes from maternal and paternal MHC are codominantly expressed
    4. β chain of MHC Class I is non-polymorphic
    5. β chain of DR is the most polymorphic region on MHC Class II
    1. The higher the number of mismatches, the lower the chance of long term survival
    2. The higher the number of mismatches, the higher the chance of graft acceptance
    3. The higher the number of mismatches, the lower the chance of chronic rejection
    4. The lower the number of mismatches, the lower the chance of long term survival
    5. Number of mismatches has no effect on long term survival

    Author of lecture Major Histocompatibility Complex (MHC) and MHC Disparity

     Peter Delves, PhD

    Peter Delves, PhD


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