Malignant Melanoma

by Carlo Raj, MD

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    Let’s talk about malignant melanoma. What are your risk factors? Sun exposure, especially at early age. Blistering sunburns in childhood is a huge risk factor. Associated with intermittent sun exposure melanoma in a first or second-degree relative also increases the risk. And you’re worried about familial type of melanoma and neoplasia. We talked about familial melanoma, familial type of malignant melanoma in which you’re worried about your patient who might be exposed to certain type of genes, huh? Including your p16(Ink) or maybe perhaps RAF, in fact B-Raf, right? And the name of the drug was vemurafenib. Those at greatest risk have light hair or red hair and light eyes. So those fair complected individuals are the ones, in which upon exposure to sun rays, are the ones that have an increased risk of going onto unfortunately malignant melanoma. New or changing mole is something that you want to keep in mind. And especially, if we're coming from a nevi such as your dysplastic nevus where we fulfill the criteria from A through E. Malignant melanoma, same as those of atypical nevi. So once, what does A mean? Asymmetry. B means border regularity C means color variegation. D means diameter greater than 6 millimeters. E is elevation. So as far as your concern, A through E, if those have been met, then high on your differential will be dysplastic nevus or you’re talking about melanoma. How do you know? We’ll talk about this further. With malignant melanoma in the skin, there is different types of growth that you want to pay attention to. What does that mean? Well remember, if cancer is to grow, what are you worried about more so? Are you more worried about invasion of the cancer into the mucosa, submucosa and then going in towards lymphatic...

    About the Lecture

    The lecture Malignant Melanoma by Carlo Raj, MD is from the course Neoplastic Skin Diseases.

    Included Quiz Questions

    1. Excision of entire lesion
    2. X-ray
    3. Complete Blood Count
    4. CT Scan
    5. Ultrasound
    1. Gastrointestinal system
    2. Liver
    3. Lungs
    4. Brain
    5. Heart
    1. Actinic lentigo
    2. Seborrheic keratosis
    3. Melanoma
    4. Compound nevus
    5. Dysplastic nevus
    1. Vertical growth of the lesion
    2. large sized lesion
    3. Radial growth of lesion
    4. Dark colored lesion
    5. Young age of the patient

    Author of lecture Malignant Melanoma

     Carlo Raj, MD

    Carlo Raj, MD

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