Malignant Liver Tumors

00:01 Hepatocellular carcinoma (HCC) A specific tumor within the liver.

00:06 Anything that causes cirrhosis, any cause of cirrhosis, you're at risk for HCC.

00:13 So, alcohol, sure.

00:17 Non alcohol, yes.

00:18 Give me two major differentials of non-alcoholic issues.

00:23 Autoimmune or maybe perhaps NASH.

00:26 Continue...

00:27 What about autoimmune? What about Hemochromatosis? What about a whole holes of differentials that may result in cirrhosis.

00:35 Hepatitis C.

00:39 Imaging sufficient with background cirrhosis.

00:42 And that background cirrhosis means what to you? Where fibrosis kicking in, tell me the size of the liver versus the original size, shrunken.

00:52 Biopsy, not always useful.

00:54 Imaging is sometimes sufficient.

00:57 Here, with the Hepatocellular carcinoma, expect her to be increased in alpha-fetoprotein.

01:02 Metastasis to the lung, bone and brain.

01:07 So this is a primary Hepatocellular carcinoma that may have resulted, let's say, from cirrhosis and from the liver.

01:15 It might metastasis, go up to the lung, and then near the bone and near the brain.

01:20 Important areas of Metastasis.

01:22 The treatment. Obviously, resection.

01:25 Transplantation is high on that list.

01:28 You have chemo-embolization.

01:29 Maybe percutaneous, ablation, and we have sorafenib.

01:36 Metastasis.

01:38 Just like many the cancers we have discussed, at times the most common cancer of that particular organ would be Metastasis from a primary.

01:47 That is the topic for this section.

01:50 Most frequent site of metastasis is from the GI tract, limited role of the resection in case of Colorectal Cancer (CRC).

01:58 In Colorectal cancer, you need to make sure, you always check to see is to whether not it is then Metastasized.

02:04 With Colorectal cancer, our discussion earlier is when we looked at duke classification.