00:01 Hepatocellular carcinoma (HCC) A specific tumor within the liver. 00:06 Anything that causes cirrhosis, any cause of cirrhosis, you're at risk for HCC. 00:13 So, alcohol, sure. 00:17 Non alcohol, yes. 00:18 Give me two major differentials of non-alcoholic issues. 00:23 Autoimmune or maybe perhaps NASH. 00:26 Continue... 00:27 What about autoimmune? What about Hemochromatosis? What about a whole holes of differentials that may result in cirrhosis. 00:35 Hepatitis C. 00:39 Imaging sufficient with background cirrhosis. 00:42 And that background cirrhosis means what to you? Where fibrosis kicking in, tell me the size of the liver versus the original size, shrunken. 00:52 Biopsy, not always useful. 00:54 Imaging is sometimes sufficient. 00:57 Here, with the Hepatocellular carcinoma, expect her to be increased in alpha-fetoprotein. 01:02 Metastasis to the lung, bone and brain. 01:07 So this is a primary Hepatocellular carcinoma that may have resulted, let's say, from cirrhosis and from the liver. 01:15 It might metastasis, go up to the lung, and then near the bone and near the brain. 01:20 Important areas of Metastasis. 01:22 The treatment. Obviously, resection. 01:25 Transplantation is high on that list. 01:28 You have chemo-embolization. 01:29 Maybe percutaneous, ablation, and we have sorafenib. 01:36 Metastasis. 01:38 Just like many the cancers we have discussed, at times the most common cancer of that particular organ would be Metastasis from a primary. 01:47 That is the topic for this section. 01:50 Most frequent site of metastasis is from the GI tract, limited role of the resection in case of Colorectal Cancer (CRC). 01:58 In Colorectal cancer, you need to make sure, you always check to see is to whether not it is then Metastasized. 02:04 With Colorectal cancer, our discussion earlier is when we looked at duke classification.
The lecture Malignant Liver Tumors by Carlo Raj, MD is from the course Cirrhosis – Liver Diseases.
Which of the following tumor markers is characteristically increased in hepatocellular carcinoma?
Which of the following is a FALSE statement regarding hepatocellular carcinoma?
Which of the following is NOT an effective treatment for hepatocellular carcinoma?
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