Lymphadenopathy: Introduction – White Blood Cell Pathology

by Carlo Raj, MD

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    Our topic here is WBC pathology. The various lymphoid tissue that we shall take a look at in this section include the lymph node. Examples clinically of when and how the lymph node will be affected. It’s important that we walk through the anatomy of it. A few words about the spleen and the thymus, all of this dealing with leukemias and lymphomas in this section in which students tend to confuse quite a bit. But by the time we are done, you’ll be well-organized with the WBC pathology. At first, we’ll take a look at the normal lymph node. Think about the lymph node that we have in our body. Think about spread that might take place within the lymph node depending as to what kind of cancer. For example, I mentioned a few times that if it was breast cancer, a prognostic indicator there would be the axillary lymph node. Whereas if you had a male and there was lymph node involvement with either your testicular cancer or your scrotal cancer. If it’s testicular cancer, then the spread will be to the paraaortic. We’ll mention these types of spreads when the time is right. At this point, it is important for us to identify the following structures. I’d like for us to start in the middle. And by the middle, I mean the germinal center. This germinal center that you’re noticing -- indentify it please – In the middle. Responsible for B-cell type of proliferation. Quite active. Beyond that, you start getting into the cortex, so this will be outer side. And we have paracortex. The paracortex will be the area in which the T-cells are housed. You have the subcapsular sinus and this sinus will become important to us at some point when we talk about a...

    About the Lecture

    The lecture Lymphadenopathy: Introduction – White Blood Cell Pathology by Carlo Raj, MD is from the course Lymphadenopathy – White Blood Cell Pathology (WBC).

    Included Quiz Questions

    1. Bacillary angiomatosis
    2. Bacillary peliosis
    3. Botryomycosis (pyoderma vegetans)
    4. Tropical pyomyositis
    5. Leptospirosis
    1. Bartonella henselae
    2. Bartonella rochalimae
    3. Bartonella quintana
    4. Bartonella vinsonii
    5. Bartonella bacilliformis
    1. Pharyngitis
    2. HIV
    3. Autoimmune diseases
    4. Drugs
    5. Cancers

    Author of lecture Lymphadenopathy: Introduction – White Blood Cell Pathology

     Carlo Raj, MD

    Carlo Raj, MD

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