00:03
Our topic here is lichen planus.
00:06
Be very careful.
00:08
I have described to you a condition
called lichen simplex chronicus.
00:16
Do not confuse one
with the other.
00:18
In lichen planus, thought to
be an autoimmune phenomenon.
00:23
Associated with hepatitis C
in areas of high prevalence.
00:27
Memorize that.
00:29
With lichen planus, you automatically
pay attention to letter P.
00:36
And with that P,
it will give you the clinical pearls of your
particular morphology of lichen planus;
purple pruritic polygonal that
will coalesce and form plaques.
00:49
The five Ps with lichen planus.
00:55
Not to be confused with
lichen simplex chronicus.
01:01
Common in the wrists and hands.
01:04
So, you would have this purple polygonal,
and then you have your papules
that are going to
coalesce and form plaque,
and can also occur in the oral.
01:13
This can be oral or genital mucosa
If you take a look at
this morphology here,
you’ll notice that we have
not only a purplish papule
on the perimeter or periphery,
but then as you come closer, polygonal
and it coalesced to form a?
Plaque.
01:36
Autoimmune in nature,
PPPPP.
01:41
Pathology: band-like
inflammation,
destruction of the
keratinocytes,
and at the
dermoepidermal junction,
okay?
Lichen planus.
01:54
Management: Limited disease treated
with potent topical steroids.
01:59
You have antihistamines may show to
help with the pruritus, that's it.
02:04
Extensive skin/mucosal disease
may require oral steroids.
02:08
And mucosal involvement is a
sign of more of a recalcitrant
and a longer lasting disease,
which is not a good sign.
02:16
Remember the one that I described
in the mouth,
Wickham's striae
Consultation with a dermatologist
or dentist is often recommended
so that you know as to what to do
with your patient cosmetically.