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So, who is affected? It's a remarkably common disease, 1 in 4 adults is affected by
hypertension. As I talk about, the risk increases with age and this probably has a lot to do
with increasing rigidity or stiffness of the aorta. 65% of men and 75% of women will have
hypertension by the time they're 70 years of age. And although I'm not quite there,
I have hypertension. Fortunately, I'm treated so I feel fine. The rates are highest in
African Americans and lowest in Asian Americans. If you're less than 45 years of age,
the most common personnel with hypertension is a woman. After 45 years of age, the
sex ratio becomes relatively equal. So, other risk factors, things that you can't do
anything about. Positive family history, hypertension as you can imagine because of the
small genetic polymorphisms tends to occur and reoccur in families. So a positive family
history, ethnicities or I said African Americans, are more prone to hypertension versus
Asian Americans. And advancing age can't do a darn thing about any of those. Things
that you can affect are obesity, diabetes, smoking, excessive alcohol or caffeine intake,
high sodium intake, low potassium intake, physical inactivity, psychological stress. So all
these things you can potentially impact. And in event that's not effective, then you can
always take antihypertensive meds. So, what is hypertension. We've been talking about
it. Now for about 30 minutes, what is it? Oh my gosh. Okay, so a normal blood pressure is
considered to be a systolic blood pressure less than 120 mmHg and a diastolic blood
pressure less than 80 mmHg. So that's kind of normal. This is a little bit of a moving target
and in some current formulations 110/70 is considered to be normal blood pressure or
upper limits of normal. Elevated, for the most part, is somewhere between 120 to 180
mmHg systole and 80-120 mmHg diastole. And then hypertensive crisis where you need
to do something immediately you're going to suffer a stroke. That's blood pressures in
excess of 180 mmHg systolic and excess of 120 mmHg diastolic. There is an entity probably
related to stress and anxiety that is at a factitious form of hypertension so called white
coat hypertension. It's seen in the clinical setting. So you go to see your doctor, they
show up with a stethoscope and white coat and you get a little anxious and your blood
pressure goes up. It's a normal response but it may be an artifactually high blood pressure
caused by anxiety. So what do you do if you suspected that's the case? Well, you can
do blood pressure measurements several minutes apart theoretically after the people
have calm down, you can do it on several different visits. In fact, you should not make a
diagnosis of hypertension on your first visit. You need to see it recurrently over time.
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You can have ambulatory blood pressure monitoring or you can have the patient just
periodically take the blood pressure themselves. The machines, the sphygmomanometers
that can do this are reasonably cheap and most motivated patients will be only too happy
to take their blood pressure at home.