Hydatidiform Mole

by Carlo Raj, MD

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    Our next topic is hydatidiform mole. What exactly is the mole? And what are we referring to? Or big picture? Our section here is placental pathologies. That’s exactly what’s going on. It’s the placenta that is going to then – Well, let me show you different characteristics. We’ll take a look at partial and complete mole. The mole refers to the fact of how much of the placenta is being affected and whether or not you’ll actually find fetal remnants within the placenta. Presents in fourth to fifth month of pregnancy, so relatively early in pregnancy. There’d be vaginal bleeding in both partial and complete as we shall see. Uterus that is larger than expected for duration of pregnancy. The gestational age in which you would expect full uterine size size is much, much greater in hydatidiform mole. This particular picture that you’re seeing here would be that in which all of the chorionic villi have now become inflamed or dilated. All, every single finger-like projection of the chorionic villi, which is part of the placenta, has now become dilated. If every single chorionic villi has then become dilated, then you have to call this a complete hydatidiform mole. What is the name of the cancer that may then take place of the placenta? That is called choriocarcinoma. So there are two types that we’ll take a look at with hydatidiform mole, complete and partial. The “C” in complete has a greater risk of going onto “C”, choriocarcinoma. Every single chorionic villi has now become dilated. What else do you want to keep in mind? The chromosomes. So what’s a normal chromosome? Obviously, either 46 XX or 46 XY. If it’s a complete mole, you’ll find that there is actually normal chromosomes, 46 XX or 46 XY. How is that...

    About the Lecture

    The lecture Hydatidiform Mole by Carlo Raj, MD is from the course Pregnancy Complications.

    Included Quiz Questions

    1. Presentation in the 2nd to 3rd month of pregnancy
    2. Vaginal bleeding
    3. Extremely high beta-hCG
    4. Passage of grape-like tissue from vagina
    5. Uterus larger than expected for gestational age
    1. Snowstorm pattern
    2. Double decidual sac
    3. Heterogenous uterus
    4. Non-homogenous echoic pattern
    5. Pseudosac
    1. High risk for choriocarcinoma
    2. Triploid chromosome
    3. Some villi are edematous
    4. Fetal parts
    5. 2 sperms and one egg
    1. Triploid chromosome
    2. High risk for choriocarcinoma
    3. All villi are edematous
    4. No fetal parts
    5. 2 sperms with no egg

    Author of lecture Hydatidiform Mole

     Carlo Raj, MD

    Carlo Raj, MD

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