An important understanding of
Hepatorenal Syndrome is required.
This is a functional renal failure
without underlying renal pathology.
This is not nephralic syndrome,
this is not nephrotic syndrome
nor it is arteriosclerosis taking
place at the renal artery.
The perfectly functional kidney,
used to be
the patient developed
there is a functional renal failure
Is that clear?
Very interesting. Important?
Type I: Severe with rapid renal failure.
your GFR drops, mortality
So, from now on,
whenever you have portal
hypertension, you can now go beyond,
just cure hepatic portal
hypertension, can't you?
An important topic.
Type II: Insidious drop in GFR.
Diagnosis of exclusion.
Here, you'll find that urine
is less than 10mEq/L urine
sodium is less than 10mEq/L
It means to say,
it is not able to properly
take care of sodium handling.
There is no established therapy
which makes it really dangerous.
And after transplantation of liver,
it seems as though the kidney
actually comes back to life.
Fascinating. We don't know a whole
lot about it but we know just enough,
where that statistic of 100% mortality
puts it on the radar, big time.