Haemophilus Ducreyi

00:01 Now, let's shift to Haemophilus Ducreyi which is much less common thankfully.

00:06 It is a cause of the sexually-transmitted infection known as chancroid.

00:10 Chancroid is symptomatic in males and as you can see from the projected image, you could imagine why that would be.

00:18 Chancroid, when it occurs, in females, is quite asymptomatic.

00:22 The pathogenesis of Haemophilus ducreyi has to do with Pili which will attach to underlying genital and perianal mucosa.

00:31 Clinical manifestations, Haemophilus Ducreyi and chancroid is a cause of one of the painful ulcers of the genitals.

00:40 Unlike some other causes which we'll talk about in other parts of these series which cause painless ulcers of the genitals, chancroid is painful.

00:49 In five to seven days after exposure to the organism and starting to develop those painful ulcers on the genitalia, then a local or regionalized lymph reaction via inguinal lymphadenopathy will develop.

01:05 Because this is a rapid onset of swollen lymph nodes, those lymph nodes will be tender.

01:12 They're stretching the capsule of the lymph node in which are residing the pain fibers.

01:17 Diagnosis largely is a diagnosis of exclusion.

01:21 Primary syphilis and herpes simplex are very common causes although more often than not, may cause painless lesions.

01:30 If one can exclude those clinically, then treatment for chancroid with Haemophilus ducreyi is accomplished with ceftriaxone and azithromycin.

01:40 So we have two different manifestations of two different types of Haemophilus.

01:46 One, very common, one, thankfully somewhat unusual.

01:50 The Haemophilus influenzae, however, as the common cause of many sinopulmonary infections is absolutely something to be aware of and to think about when making typical diagnosis.

02:02 Here ends the story on Haemophilus.