00:01
Now, a very serious form, this
high altitude cerebral edema.
00:07
This can occur with
things like confusion,
ataxia, mood changes,
hallucinations and even coma.
00:12
So you can imagine if you
were a mountain climber,
and if you were ataxic
and hallucinating,
your chances of making an
error are much higher.
00:20
So high altitude cerebral edema
can not only be life-threatening
from an injury point of view, but
also from the cerebral edema.
00:32
What are the causes of pathophysiology
of high altitude cerebral edema?
Well, it seems that the cerebral edema
occurs because of an increase in blood flow.
00:40
As well as an increase in permeability
of the blood-brain barrier.
00:44
What happens here is
some of the substances
move out of the blood vessels into the
cerebral tissue and then swell that tissue.
00:55
And this example of this
photograph is an autopsy
where it can show this cerebral edema in
some who had high altitude cerebral edema.
01:04
Normally, where you see these
lines in this brain tissue,
these should be deep sulci which means
that they should be little valleys.
01:11
Here, they are flattened out.
01:17
Now how do you prevent and treat
high altitude cerebral edema?
Well, of course, prevention
is always the best way
and similar to acute
mountain sickness,
part of this involves gradual
ascending to that new environment.
01:29
There is some pharmacology
that sometimes can help.
01:32
Corticosteroids, which
decrease inflammation,
could be a benefit to
decrease swelling.
01:40
But really, the most important
thing is that any of these
symptoms of high altitude
cerebral edema are viewed,
you need to get the person
off of the mountain
and so you need to descend them
to a lower barometric pressure.
01:53
If that’s not possible, they’ve
even come up with some specialized,
what looks like a
large sleeping bag
in which you can pump up the
pressure in the sleeping bag
to create an artificial
pressure environment.
02:04
And that type of environment
can sometimes be enough
to decrease the amount of
high altitude cerebral edema.