Need you to leave behind Gastric Adenocarcinoma.
But another type of cancer that you need to know for
the stomach would be Gastric Lymphoma. They
accompany majority of the remaining gastric cancers.
Here, known as a MALToma. Now keep in mind when you
say lymphoma, it could be either T or B type.
I'm going to to make it easier for you. If you're
on the skin, that would be a T−type of lymphoma.
Cutaneous T−Cell Lymphoma. You've heard of Sezary
syndrome, that's a T−cell lymphoma. You've heard of
Adult T−Cell leukemia and lymphoma, right?
So all of those would be cutaneous T−cell lymphomas.
Whenever you have issues within an organ,
especially the gut, that will be a B−cell lymphoma.
In fact, when we did WBC pathology and we talked about
leukemias and lymphoma. There in fact we did diffuse
large B−cell lymphoma and which is a non−Hodgkin's
lymphoma which loves to go or more commonly
would be extranodal. Isn't the
stomach tissue extranodal?
Yeah. And yet you're developing a lymphoma? Yes. Because
of the amazing and incredibly intense immune reaction
that you would have of the B−cell type to the
H. pylori in the chronic fashion literally looking
like a lymph node in your mucosa-associated lypmhoid
tissue, tissue, tissue. That's your full story of a
B−cell type of lymphoma in your stomach
tissue resulting from chronic H. pylori.
Generally speaking, with gastric lymphoma, they
comprise the majority of remaining gastric cancer.
We talked about biopsy usually obtained by upper
endoscopy. H. pylori associated lymphoma,
treatment of the infection may lead to resolution of
lymphoma. So the regimen that I had given you earlier
with H2 blockers and your antibiotics such as
clarithromycin and such. By giving antibiotics,
amazing, that you're able to actually cure a cancer.
Gastric lymphomas are more sensitive to radiation
therapy than are gastric adenocarcinomas.