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Factors Affecting Drug Metabolism – Biotransformation | Pharmacokinetics (PK)

by Pravin Shukle, MD
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    About the Lecture

    The lecture Factors Affecting Drug Metabolism – Biotransformation | Pharmacokinetics (PK) by Pravin Shukle, MD is from the course Pharmacokinetics and Pharmacodynamics. It contains the following chapters:

    • Factors Affecting Drug Metabolism
    • Interactions of CYP450
    • Inhibitors & Inducers of CYP 450
    • P-Glycoprotein Inhibitors
    • Case Study: Drug Interaction in the CCU
    • Questions and Case Study

    Included Quiz Questions

    1. experience lower drug levels than a heterozygote.
    2. experience prolonged activity when compared to a person with no active alleles.
    3. experience higher drug concentrations and prolonged drug activity than a heterozygote.
    4. experience higher drug concentrations and shortened activity than a heterozygote.
    1. the drug is administered with a cytochrome inducer.
    2. The drug is given to a patient with few active metabolic alleles.
    3. The drug is given to a patient who cannot metabolize the drug.
    4. The drug is given to a patient who had ingested a suicide inhibitor of cytochrome.

    Author of lecture Factors Affecting Drug Metabolism – Biotransformation | Pharmacokinetics (PK)

     Pravin Shukle, MD

    Pravin Shukle, MD


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