A well oiled machine has hundreds of parts
all working together in a unison
to accomplish the functions of a machine.
For a cell ideally metabolic control
is working like a well oiled machine
and that's the focus of this presentation.
In this talk, I will discuss energy
considerations relative to cellular needs,
futile cycles, reciprocal regulation, the cori cycle,
and finally, hormonal control, how
everything integrates together.
Now cells have needs for energy.
There are times when they need
to make ATP and there are times
when they have plenty of ATP.
Catabolic processes which are the break down processes,
generate energy for cells and they
harvest that energy in the form of ATP.
Catabolic processes are ideally
active in circumstances of low energy
and inactive in circumstances of high energy,
so as not to waste that energy.
Anabolic processes are the opposite.
They require input of energy and
so it’s ideal if they are active
when the high energy state of the cell exists
such as when there is plenty of ATP.
And they are inactive in circumstances of
low energy when there is, of course, low ATP.