Closer look at each of the components of this
endomembrane system, endomembrane transport system.
The first piece recall is the endoplasmic reticulum.
I've always loved that word.
It has two components.
We've got the smooth and the rough endoplasmic reticulum.
The rough endoplasmic reticulum is rough because
it has ribosomes on it.
Because it has ribosomes on it,
we know it's associated with the manufature of proteins
and these are manufacturing proteins to go.
The other component is the smooth endoplasmic reticulum.
And the smooth endoplasmic reticulum
has a little bit different of a function.
It can produce lots of membrane because it is made of phospholipids.
Recall, all of these endomembrane system is phospholipid bilayer.
A single layer now. But phospholipid bilayer nonetheless.
And so the smooth endoplasmic reticulum can produce
a lot of itself and it's actually also involved in detoxification.
So for example, a liver cell would have a lot of smooth
endoplasmic reticulum because it's involved in detoxification.
You can actually see after a big night on the town,
or perhaps you've had one or too many cocktails,
the liver cells will produce extra endoplasmic reticulum.
And on the micrograph you can see that, and we call that fatty liver.
So extra alcohol consumption, extra detoxification necessary,
lots more endoplasmic reticulum.
So moving on from there,
we see the Golgi apparatus is the next step in the game.
We said this is the shipping center.
Again it has a cis face and a trans face
The cis face is the arrival side, that's where you are dropping off
your packages that you've just made in your production center.
We drop off the packages on one side, and they are taken in
by endocytosis, the materials are pulled into the Golgi apparatus.
And then they are repackaged and labelled and addressed
and put in the correct vans to be sent out on the trans face.
I do remember those because
trans is about transport, transporting away.
And cis, well, that's arrival, because it's not transport.
And then we end up having our vesicle, which is our little van.
Van, vesicles, going all the way to the external cell membrane
and we will drop off the contents of the cell
on the external cell membrane.