Dopamine Agonists and Prolactinomas in Pregnancy

by Lynae Brayboy, MD

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    About the Lecture

    The lecture Dopamine Agonists and Prolactinomas in Pregnancy by Lynae Brayboy, MD is from the course Reproductive Endocrinology. It contains the following chapters:

    • Dopamine Agonists & Prolactinomas in Pregnancy
    • Case Studies

    Included Quiz Questions

    1. MEN -1
    2. MEN - 2A
    3. MEN -2B
    4. Cowden syndrome
    5. Turcot syndrome
    1. Dopamine antagonists
    2. Bromocriptine
    3. Cabergoline
    4. Transsphenoidal surgery
    5. Radiation
    1. Restart bromocriptine
    2. Perform transsphenoidal surgery
    3. Provide radiation
    4. Check prolactin levels to confirm increase in size
    5. Prescribe cabergoline
    1. Minimise the dose of dopamine agonists before the referral of surgery.
    2. MRI can be performed to visualize prolactinomas in pregnant women.
    3. Prolactin level in pregnancy with prolactinoma is not useful for the diagnosis.
    4. Breast feeding is contraindicated in patients who are on dopamine agonists.
    5. Radiation is NOT a relevant option as a treatment for macroadenomas in patients who are pregnant.
    1. Repeated measurements of the hormone levels will provide accurate measurement
    2. Dilution helps to obtain the appropriate values in hormones that are affected by a hook effect.
    3. Hook effect is not restricted only to prolactin hormone.
    4. The hormone is in high concentrations that it gets attached to the antibodies that provide a signal and is unable to bind to the immobilized antibodies on the surface.
    5. Hook effect is when the hormone is so largely elevated that the test results as false negative.

    Author of lecture Dopamine Agonists and Prolactinomas in Pregnancy

     Lynae Brayboy, MD

    Lynae Brayboy, MD

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