So now we have seen this epinephrine
glucagon insulin pathway
regulating the most important energy producing
or energy storing molecules in the cell.
This coordination of activities that you have seen
is very important and let's go through that one more time.
Insulin is stimulating the uptake of glucose; because,
glucose concentration high in the blood stream is a problem.
Epinephrine is favoring the opposite process which
is the stimulation of the production of glucose
from the liver; because, the body has low
blood glucose levels and needs them.
Insulin stimulates glycolysis which is
the use of glucose and it stimulates
glycogen synthesis which is
also using that glucose.
Thereby keeping the intracellular
glucose concentration also low.
So not only is insulin favoring the
lowering of the glucose in the blood,
it's favoring the use of that glucose inside
of the cells so that it doesn't cause problems.
Epinephrine glucagon, by contrast, stimulates
gluconeogenesis and glycogen breakdown; because,
it's favoring the release of glucose from the cell.
Insulin stimulates the dephosphorylation
of the enzyme making fatty acids,
acetyl-CoA-carboxylase and therefore favors
fatty acid synthesis and by extension, fat.
Epinephrine and glucagon stimulates the
activity of the enzyme that breaks down fat,
triacylglycerol lipase and
favors fatty acid release from fat.
Now these many events are
coordinated in this one slide here,
so I am not gonna through the
entire slide and talk about that.
But so far as I say that epinephrine
is favoring the breakdown
of molecules to either release glucose or favor
energy; because, when it favors the breakdown of fat
it's favoring energy for
the body which is needing energy.