00:01 Let’s move on to syphilis. 00:03 Syphilis is caused by the spirochete, Treponema pallidum. 00:08 In the United States, we are having currently a rising epidemic of syphilis. 00:14 The highest transmission to the fetus is if the mother has secondary syphilis. 00:20 Primary syphilis is less likely to transfer, but it still can. 00:24 So if a mother has secondary syphilis, we worry about that baby. 00:29 The baby can present with a variety of symptoms. 00:33 They may be asymptomatic or they may be dead on presentations. 00:37 So stillbirth is possible, but also, more than 60% will be completed asymptomatic at birth. 00:44 But watch out, they may later present with a second or a third staged disease syphilis. 00:52 So a child may be asymptomatic at birth, and then at few years of age, develops secondary syphilis. 00:59 So early findings in syphilis include hepatosplenomegaly, lymphadenopathy, rash, a rhinitis or syphilitic snuffles, or they may have metaphyseal lucencies on radiography. 01:14 That can be a classic x-ray finding. 01:17 Later findings include Hutchinson teeth, which are notched teeth. 01:24 Hearing loss, a saddle nose deformity, or Saber shins, which are sharpened shins in the front from hematopoiesis. 01:35 Or they may also get developmental delay.
The lecture Congenital Syphilis by Brian Alverson, MD is from the course Neonatology (Newborn Medicine).
What percent of newborns with syphilis are asymptomatic?
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