# Combination of Cardiac and Vascular Function Curves – Regulation of Venous Pressure

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03:58 Let's take another example for this. How about if you had an individual that lost fluid? Maybe through something like a hemorrhage. So if they had a hemorrhage they lost a little bit of fluid but were able to then clot their blood so that they didn't lose any more fluid. Could the heart respond to try to maintain enough cardiac output? With these vascular function curves you can see that occur. So the first thing that happens if we started at the equilibrium point in a normal condition, a decrease in blood volume would have it travel down the curve to a new equilibrium point at a lower blood volume. How do you fix that response? You need to increase contractility or inotropy and you do that by a cardiac function curve change. What happens is the cardiac function curve gets shifted upwards and to the right and that allows to return cardiac output to its normal level. Notice though as you move cardiac output up to this new equilibrium point, that central venous pressure decreases. So you have to always look at both variables, central venous pressure and cardiac output to make sure you understand how the body is trying to respond to either a change in a cardiac curve or a change in a vascular function curve. I invite you to play with these scenarios so that you get a good feel for if you have increases in blood volume, decreases in blood volume, changes in the cardiac function curve of decreasing or increasing and how the body would then try to adapt to such a response.

The lecture Combination of Cardiac and Vascular Function Curves – Regulation of Venous Pressure by Thad Wilson, PhD is from the course Vascular Physiology.

### Included Quiz Questions

1. 5 liter/min.
2. 1 liter/min.
3. 2 liter/min.
4. 3 liter/min.
5. 4 liter/min.
1. Increase volume.
2. Increase force of contraction.
3. Increased heart rate.
4. Increased conduction.
5. Decrease volume.
1. Increase Inotropy.
2. Decrease central venous pressure.
3. Decrease conduction.
4. Decrease heart rate.
5. Vasodilatation of vessels.