CNS Infections: Introduction

by Carlo Raj, MD

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    00:01 Hello! Let’s continue taking a look at neuropathology.

    00:05 Here, the overall theme would be CNS infections.

    00:08 With CNS infections, these are topics that we’ll take a look at.

    00:12 For the most part, it comes under microbiology.

    00:15 And what is the pathologic approach that you want to take with CNS infections will be the overall theme.

    00:22 We’ll walk through quickly some bacterial, viral, fungal; mycobacterial referring to tuberculosis; spirochetes, referring to you the Lyme disease; parasitic and, ultimately, prion disease.

    00:36 Prion itself, as you know, in microbiology, there’s a lot of research in terms of how it behaves.

    00:42 It’s quite interesting because it is considered to be contagious, but nonetheless, it’s difficult to understands the behavior of this prion disease as you’ve heard of mad cow disease for an example.

    00:57 The classifications we’ll take a look at under meningitis is, as I said, the overall theme for this is going to be CNS infections.

    01:04 But under meningitis, apart from the infections agents maybe bacterial, viral or fungal, whatnot, there will be other causes of meningitis that is not so much infectious, just keep that in mind as we walk through more of these issues.

    01:21 Now, what’s the difference between meningitis and encephalitis? Well, from neuroanatomy, remember that the meninges, well, if they undergo infectious changes, that it undergoes an inflammatory process.

    01:34 And then of course, the lumbar puncture and the evaluation of your cerebrospinal fluid becomes incredibly important.

    01:41 But what’s underneath the meninges, what’s underneath that pia matter? Oh yeah, you have the brain parenchyma.

    01:48 What if the brain parenchyma then becomes injured and undergoes an inflammatory process? Well, at this point, you call this encephalitis.

    01:57 And we’ll take a look at various causes of encephalitides.

    02:01 Myelitis, referring to your spinal cord.

    02:04 And then, quickly walk you through some important abscess information.

    About the Lecture

    The lecture CNS Infections: Introduction by Carlo Raj, MD is from the course CNS Infection—Clinical Neurology.

    Included Quiz Questions

    1. Chemical meningitis
    2. Prion causing meningitis
    3. Spirochete causing meningitis
    4. Bacterial meningitis
    5. Parasitic meningitis
    1. Spinal cord
    2. Brain parenchyma
    3. Pachymeninges
    4. Leptomeninges
    5. Subarachnoid space

    Author of lecture CNS Infections: Introduction

     Carlo Raj, MD

    Carlo Raj, MD

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