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Cell Cycle: Cyclin D – Carcinogenesis

by Carlo Raj, MD
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    About the Lecture

    The lecture Cell Cycle: Cyclin D – Carcinogenesis by Carlo Raj, MD is from the course Cellular Pathology: Basic Principles.


    Included Quiz Questions

    1. ERB-1
    2. E2F
    3. Rb
    4. CDK4
    5. Cyclin D
    1. Compaction of chromatin
    2. Increased transcription
    3. Rapid movement from G1 to S phase
    4. Upregulation of E2F/DP1/RB complex
    5. Decreased phosphorylation of E2F
    1. p21
    2. MDM2
    3. CDK4
    4. p16
    5. p14
    1. Increased phosphorylation of Rb
    2. Inhibition of Cyclin D/CDK4 complex
    3. Increased p53 activity
    4. Upregulation of E2F
    5. Decreased free E2F
    1. Decreased available CDK2
    2. Decreased transcription of Cyclin E
    3. Decreased transcription of Cyclin A
    4. Increased dephosphorylation of Rb
    5. Increased E2F/DP1/Rb complex
    1. p27
    2. p53
    3. p14
    4. p16
    5. MDM2

    Author of lecture Cell Cycle: Cyclin D – Carcinogenesis

     Carlo Raj, MD

    Carlo Raj, MD


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