Lectures

Cardiac Function and Anesthesia – Respiration and Cardiovascular System

by Brian Warriner, MD
(1)

Questions about the lecture
My Notes
  • Required.
Save Cancel
    Learning Material 2
    • PDF
      02 - Respiration and Cardiovascular System.pdf
    • PDF
      Download Lecture Overview
    Report mistake
    Transcript

    00:00 patients with unstable cardiac disease. So how about the cardiovascular system? Does general anesthesia have an impact upon cardiac function? How about the anesthetic vapours? Some anesthetic vapours can reduce the contractility of the heart and reduce cardiac output. These tended to be the older vapours such as Halothane, but modern vapours such as Isoflurane, Desflurane, and Sevoflurane have little or no effect upon cardiac contractility.

    00:25 They do unfortunately, or fortunately depending on the situation, have an impact upon peripheral resistance, which is the resistance against which the heart has to work when it contracts. And low peripheral resistance may result in low blood pressure, but it may also allow the heart to contract more fully. So there's a balance all the time, trying to maintain it just right. If you reduce blood flow too much, you can reduce it to the brain, the kidney, and the heart itself. Obviously, not a good thing. Opiates and opioids have little of direct effect upon the heart, other than they slow heart rate, which in most cases is a very positive situation. They also have a moderate effect on lowering blood pressure. The changes are moderate, and they have very few side effects.

    01:19 Induction drugs, unfortunately, are much more problematic. The most popular induction drugs are Thiopentone and Propofol. Both of these have profound effects on reducing cardiac contractility. In addition, Propofol causes marked reduction in peripheral resistance, thus potentiating hypotension, and sometimes leading to reduced blood flow to vital organs, including the heart. This graph


    About the Lecture

    The lecture Cardiac Function and Anesthesia – Respiration and Cardiovascular System by Brian Warriner, MD is from the course Anesthesiology: Introduction.


    Author of lecture Cardiac Function and Anesthesia – Respiration and Cardiovascular System

     Brian Warriner, MD

    Brian Warriner, MD


    Customer reviews

    (1)
    5,0 of 5 stars
    5 Stars
    5
    4 Stars
    0
    3 Stars
    0
    2 Stars
    0
    1  Star
    0