Traumatic Brain Injury: Chronic Traumatic Encephalopathy

by Roy Strowd, MD

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    00:01 Let's talk just a little bit about Chronic Traumatic Encephalopathy.

    00:04 This is the really feared and concerning long term risk in patients who have had multiple concussions and subconcussive injuries over time.

    00:14 Chronic Traumatic Encephalopathy is the long-term pathology that results from repeated traumatic brain injuries and is termed CTE.

    00:25 The neuropathological features of CTE are hypothesized to be a tauopathy.

    00:31 But this condition continues to be described and really, we see two things contributing to CTE.

    00:37 One is repeated traumatic brain injuries, or concussions, and also a long period of subconcussive micro injuries that can also contribute to this pathology.

    00:50 What are some of the clinical features? We see a range of symptoms that can characterize a chronic chronic traumatic encephalopathy, behavioral disturbances like aggression and impulsivity, mood disturbances, anxiety, depression, suicidal ideations and cognitive impairments.

    01:06 And we worry about each of these evaluating those in patients who have experienced prior traumatic brain injury.

    01:15 In terms of evaluation, histopathologic diagnosis is rare in this condition and is really defined by autopsy.

    01:22 There are no biomarkers, lab findings, imaging findings that are specific to CTE.

    01:27 We're using our clinical examination to guide evaluation and diagnosis of this condition and treatment is preventive and supportive.

    01:35 We look to decrease the number of traumatic injuries to the brain concussions, and optimize supportive care for the symptoms that arise from this condition.

    About the Lecture

    The lecture Traumatic Brain Injury: Chronic Traumatic Encephalopathy by Roy Strowd, MD is from the course Head Trauma.

    Included Quiz Questions

    1. Chronic traumatic encephalopathy
    2. Encephalomalacia
    3. Lissencephaly
    4. Normal pressure hydrocephalus
    5. Diffuse axonal injury
    1. Behavioral and mood disturbances
    2. Focal neurologic deficits
    3. Neck stiffness
    4. Photophobia
    5. Coma

    Author of lecture Traumatic Brain Injury: Chronic Traumatic Encephalopathy

     Roy Strowd, MD

    Roy Strowd, MD

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