00:01 Let's talk just a little bit about Chronic Traumatic Encephalopathy. 00:04 This is the really feared and concerning long term risk in patients who have had multiple concussions and subconcussive injuries over time. 00:14 Chronic Traumatic Encephalopathy is the long-term pathology that results from repeated traumatic brain injuries and is termed CTE. 00:25 The neuropathological features of CTE are hypothesized to be a tauopathy. 00:31 But this condition continues to be described and really, we see two things contributing to CTE. 00:37 One is repeated traumatic brain injuries, or concussions, and also a long period of subconcussive micro injuries that can also contribute to this pathology. 00:50 What are some of the clinical features? We see a range of symptoms that can characterize a chronic chronic traumatic encephalopathy, behavioral disturbances like aggression and impulsivity, mood disturbances, anxiety, depression, suicidal ideations and cognitive impairments. 01:06 And we worry about each of these evaluating those in patients who have experienced prior traumatic brain injury. 01:15 In terms of evaluation, histopathologic diagnosis is rare in this condition and is really defined by autopsy. 01:22 There are no biomarkers, lab findings, imaging findings that are specific to CTE. 01:27 We're using our clinical examination to guide evaluation and diagnosis of this condition and treatment is preventive and supportive. 01:35 We look to decrease the number of traumatic injuries to the brain concussions, and optimize supportive care for the symptoms that arise from this condition.
The lecture Traumatic Brain Injury: Chronic Traumatic Encephalopathy by Roy Strowd, MD is from the course Head Trauma.
What is the term for the long-term pathology that results from repeated traumatic brain injuries?
What symptom is seen in patients with chronic traumatic encephalopathy?
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