Baroreceptor Reflex – Regulation of Ambulatory Blood Pressure (ABP)

by Thad Wilson, PhD

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    Now we're going to discuss the regulation of arterial blood pressure. The best way to talk about the regulation of blood pressure is through very acute or fast changes in arterial pressure. These are best sensed by a baroreflex-mediated response. The baroreflex is going to involve a sensor, the baroreceptor, some integration in the brainstem through cardiovascular control centers and then an effect. So let's talk through some of these right now. The cardiovascular control centers involve both an input and an output region. So let's go through an example. If you have an increase in arterial blood pressure, that's going to be sensed by the baroreceptors sending a positive signal of high blood pressure to the input centers of the cardiovascular control center. There are three primary inputs that you're going to sense. They are going to affect the cardioinhibitory center, the cardioacceleratory center and the vasomotor center. In this case when we have an increase in blood pressure, you're going to stimulate the cardioinhibitory, you're going to inhibit the cardioacceleratory and you're going to inhibit the vasomotor centers. What physiological effect happens by stimulating these control centers? You have a decrease in heart rate, a decrease in inotropy which is contractility of the heart, a decrease in preload. All of those combine together to decrease cardiac output. Then along with the vasomotor center inputs the decrease in cardiac output you get an overall decrease in blood pressure. This is a classic baroreflex response. If you have an increase in blood pressure, how you get a lowering of that blood pressure? The opposite also occurs. If we went through the same example when we start it off with a decrease in blood pressure, this is how it would look. You would have a decrease in arterial blood pressure which...

    About the Lecture

    The lecture Baroreceptor Reflex – Regulation of Ambulatory Blood Pressure (ABP) by Thad Wilson, PhD is from the course Vascular Physiology.

    Included Quiz Questions

    1. Cardioinhibitory
    2. Vasomotor
    3. Cardioacceleratory
    4. Sudomotor
    1. Carotid artery
    2. Superior mesenteric artery
    3. Temporal artery
    4. Internal jugular vein
    5. Middle meningeal artery
    1. Vagus
    2. Glossopharyngeal
    3. Abducent
    4. Occulomotor
    5. Trigeminal

    Author of lecture Baroreceptor Reflex – Regulation of Ambulatory Blood Pressure (ABP)

     Thad Wilson, PhD

    Thad Wilson, PhD

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