00:01
Students often have a hard time with
autoimmune hemolytic anemia only because
they haven’t spent enough time
with dealing with the immunology
of couple of these immunoglobulins
that we’ll take a look at.
00:12
So let’s, once and for all, bring absolute
clarity to autoimmune hemolytic anemia.
00:20
To begin with, immune
hemolytic anemia, same thing.
00:24
What’s going to end up happening here is
that with IHA (immune hemolytic anemia) --
Well, there are 2 different types
that we’ll take a look at.
00:33
Agglutination of RBCs in cold types is --
Well, by looking at this picture,
it's rather difficult for you
to figure out immediately.
00:42
However, with enough history, say the patient
is suffering from mycoplasma pneumonia
and then we will talk more about how
the patient is developing cold.
00:51
So when we do immune hemolytic anemia,
autoimmune hemolytic
anemia, there are two types.
00:57
One will be warm, the
other one will be cold.
01:00
And apart from that, most
importantly, you need to figure out
as to how to differentiate
between the two, its associations.
01:08
The last time, we even brought up anything
dealing with the immune hemolytic anemia
was actually a differential
of hereditary spherocytosis.
01:17
Do you remember that?
Why did I bring anything up there?
Well, do you remember what a hereditary
spherocytic type of RBC looks like?
A spherocyte.
01:26
do you remember the differential
that I had given you?
Good.
01:29
Warm type of autoimmune hemolytic anemia
which we haven’t look at yet, but we shall.
01:36
And in hereditary spherocytosis,
what was the test that we
conducted in which it ruled out
warm type of autoimmune hemolytic anemia?
Good.
01:46
Coombs test.
01:48
Coombs test is negative,
hereditary spherocytosis.
01:51
Coombs test is positive,
you’re looking in the realm of
autoimmune hemolytic anemia
and that would be warm though.