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Acid-base Balance (Nursing)

by Jasmine Clark

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      Slides Nursing Physiology Fluid Electrolyte and Acid Base Balance.pdf
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    00:01 pH is going to affect all of the functional proteins as well as biochemical reactions that are going to occur in our body.

    00:09 So therefore, it's very important that we regulate our body's pH.

    00:15 The normal body pH in our arterial blood is about 7.4.

    00:21 So our blood is slightly alkaline.

    00:24 Our venous blood in our interstitial fluid have a slightly lower blood pH of about 7.35.

    00:35 Inside our intracellular fluid compartment, the pH is a little closer to normal at a pH of 7.

    00:44 Alkalosis or alkalemia is a disorder in which our arterial pH rises above 7.45.

    00:55 Conversely, acidosis or acidemia, as when our blood pH is going to drop below 7.35.

    01:05 Small amounts of acidic substances are going to enter our body by way of our food all the time.

    01:11 However, most of the acid or H+ produced in our body is actually produced by by-products of metabolism.

    01:21 So for example, phosphorus-containing proteins are going to break down, and release phosphoric acid into our extracellular fluids.

    01:31 Also, during anaerobic respiration, we're going to get an increasing amount of lactic acid from glucose.

    01:40 Fatty acids and ketone bodies are going to form acids from fat metabolism.

    01:46 And also H+ is liberated from the carbon dioxide as it's converted to bicarbonate in our blood, in our bicarbonate buffer system.

    01:58 We'll discuss this a little bit later.

    02:02 So the concentrations of our hydrogen ions are going to be regulated sequentially by three mechanisms.

    02:11 First, and the most rapid or fastest and our first line of defense are going to be chemical buffer systems that are found in our body.

    02:21 Secondly, we have our brainstem respiratory centers, which are going to act very soon after the chemical buffers within about one to three minutes.

    02:33 Finally, the most potent, but the one that takes the most time are the renal mechanisms.


    About the Lecture

    The lecture Acid-base Balance (Nursing) by Jasmine Clark is from the course Fluid, Electrolyte, and Acid-base Balance – Physiology (Nursing).


    Included Quiz Questions

    1. Fatty acids and ketone bodies
    2. Phosphoric acid and lactic acid
    3. Lactic acid and fatty acids
    4. Glucose and ketone bodies
    1. Chemical buffer systems
    2. Brainstem respiratory centers
    3. Renal mechanisms
    4. Anaerobic respiration
    5. Fat metabolism

    Author of lecture Acid-base Balance (Nursing)

     Jasmine Clark

    Jasmine Clark


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