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About the Lecture
The lecture Vulvar Intraepithelial Neoplasia & Extramammary Paget´s Disease by Carlo Raj, MD is from the course Disorders of Vulva, Vagina and Cervix.
Included Quiz Questions
A 40-year-old female sex worker is diagnosed with carcinoma of the labia majora. Which of the following is the most likely histopathological appearance of this lesion's biopsy?
- Squamous cell carcinoma
- Melanoma
- Bartholin gland adenocarcinoma
- Basal cell carcinoma
- Rhabdomyosarcoma
What is the main difference between histopathology of VIN and condyloma acuminatum?
- VIN shows koilocytes and dysplasia of the squamous epithelium; condyloma shows koilocytes and hyperplasia of the squamous epithelium.
- VIN shows squamous cells invading the basal layer; condyloma shows squamous cells in a branching pattern.
- VIN shows adenomatous changes in the epithelium; condyloma shows only inflammatory changes.
- There is no difference; they can only be differentiated by identifying the viral cause.
- VIN shows koilocytes in multiple layers of squamous epithelium; condyloma shows koilocytes in only one linear layer of squamous epithelium.
All of the following is TRUE about extra mammary Paget's disease of vulva EXCEPT which of the following?
- It is a subtype of squamous cell carcinoma, and is microscopically indistinguishable from VIN.
- It most commonly occurs in old caucasian females.
- It most commonly arises from and is confined to the epidermis.
- Histologically, it appears as glandular cells within the squamous epithelium.
- Unrelenting pruritis is a common presenting symptom.
Author of lecture Vulvar Intraepithelial Neoplasia & Extramammary Paget´s Disease
Carlo Raj, MD
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