Hematology Question Set 1

A 35 year old African American male presents with a chief complaint of fever, abdominal pain and severe weakness since yesterday. Examination shows the presence of jaundice and pallor. Past history includes antimalaria prophylaxis while visiting Nigeria. Labs show a normal G6PD levels. Peripheral smear shows the presence of bite cells and Heinz bodies. What is the most likely diagnosis?

A 35 year old female presents to the outpatient unit with exertional dyspnea and fatigue for the past 3 weeks. There is increased intensity of dyspnea in the past 5 days, which brought her to check up. On examination, the mucous membranes show pallor (paleness of the skin). Auscultation showed the presence of a mid-systolic murmur at the pulmonary region. Peripheral blood smear showed microcytic and hypochromic anemia. The nutrient which is responsible for the present clinical scenario is absorbed from?

A 6-year-old boy presents to the outpatient clinic with pain and swelling in the knee joint. Examination shows erythema without petechia nor purpura. There is an absence of lymphadenopathy. There is a positive family history of bleeding disorders in his father. Hemoglobin: 12.8gm%, Hematocrit 35.4%, WBC: 8400/mm3, Platelets: 215 x 109/L ;PT :11.5 s ; aPTT is 48s which is not corrected with a 50:50 mixing studies. What is the most likely cause?

A 2-year old child had increased bleeding while circumcision. Labs results are as follows: Hemoglobin: 12.8 gm % Hematocrit: 35.4% WBC: 8400/mm3 Platelets: 215 x 109/L PT: 25 s aPTT: 48s Bleeding Time is increased. What is the most likely diagnosis?

29-year old female with systemic lupus erythematosus has developed sudden pain in his left leg that increases on walking. She also has h/o multiple abortions. O/E Homan’s sign is positive. Doppler ultrasound revealed a thrombus in left popliteal vein. Her lab results are as follows: Platelets: 250,000/cmm Prothrombin Time: 14 sec Partial Thromboplastin Time: 90 sec What is the most likely cause of patient’s condition?