Trousseau Syndrome

00:01 So, one of the manifestations of thrombophlebitis, that kind of comes and goes in various locations, this is called, “Trousseau Syndrome” or, “Migratory Thrombophlebitis.” So, “Migratory” just means, it's in one location and then it goes away, and then it's in another location, it goes away, and it's in a third location, then it goes away, that's “Migratory Thrombophlebitis,” so, that means that there's intermittent clotting in various places.

00:32 Trousseau Syndrome is, specifically, when it's associated with malignancy.

00:36 When we see migratory thrombophlebitis, 99 times out of 100, it's going to be due to malignancy.

00:43 And actually, the most common malignancies are, “Pancreatic adenocarcinoma” and “Bronchial carcinomas,” which elaborate a lot of tissue factor.

00:51 Interestingly and sadly enough, Trousseau, who was a clinician diagnosed the syndrome in himself, before he died of gastric adenocarcinoma, and so, he was having this migratory thrombophlebitis, knew that he had a cancer someplace, and then ultimately died as a result of that.